Von Willebrand Disease (VWD) is the most common inherited bleeding disorder in the United States. Despite this, however, many healthcare professionals lack the knowledge required to diagnose or treat VWD. This activity addresses the importance of long-term prophylaxis in VWD on guideline recommendations for long-term prophylaxis, and on emerging data regarding novel agents for prophylaxis in this disease. This program will conclude with case discussions designed to improve the awareness concerning symptoms of VWD and diagnostic assessments in order to better manage and treat the patients in your practice.